Microsoft provides Windows Defender pre-installed, as you probably know already. You can choose between free versions or paid ones. That brings us to the next problem, of course: what is the antivirus software that you should choose? Seriously, unless you keep the device in question offline permanently (which is unthinkable), the lack of a good antivirus suite will take away your ownership over the system in a matter of hours or less.
If you use Windows as your regular operating system, you know that antivirus software is not optional.
Read this in-depth Avast versus Windows Defender comparison to decide whether it's a good idea to ditch Microsoft's inbuilt antivirus or not.